Synthesis and reactivity of a cyclic alpha-amino diphosphonate ester. II
Synthèse et réactivité d'un ester cyclique d'alpha-aminodiphosphonate. II
Résumé
The reactions of methoxy dioxaphospholan and corresponding hydrogen phosphonate 1 with (MeN = CHCl)Cl, (MeO)2CHNMe2 and MeOCH2NMe2 have been studied. These reactions lead either to amino diphosphonate 5 or to amino phosphonate 3 and phosphate 2. The hydrolysis and methanolysis reactions of 5 are also presented.