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Dynamical resource allocation models for bioreactor optimization

Abstract : Recent advances in modeling bacterial cell functioning have deeply renewed questions about bioprocess design and opens the way towards the development of computer aided design (CAD) for strains. This article aims at explaining and exploring the consequences opened by the new cell models, investigating the questions related to the biological implementation of optimal strategies and in conclusion the possible role of the complex regulatory network in the retuning of the strain.
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Guillaume Jeanne, Anne Goelzer, Sihem Tebbani, Didier Dumur, Vincent Fromion. Dynamical resource allocation models for bioreactor optimization. 7th. International FOSBE 2018 - Foundations of Systems Biology in Engineering, Aug 2018, Chicago, United States. ⟨10.1016/j.ifacol.2018.09.020⟩. ⟨hal-02736921⟩

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