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Diversité génomique de porcs issus d’un croisement Large-White x Piétrain

Abstract : One of the expected benefits of crossbreeding, a common practice in the pig industry, may be the increase in genetic variability, especially in a context of creation of synthetic populations. This increase in variability, related to the heterozygous status of individuals, remains difficult to specify when only genealogical information is available. It is now possible to characterize genetic variability in pig populations at a genome scale by analyzing genotypic data. One possible approach is to detect homozygous regions along the genome to quantify genomic consanguinity in an individual. These homozygous regions can be quantified at the genome or chromosome scale. It is then possible to characterize both overall genomic consanguinity of an individual or a local one in specific areas of the genome. In this study, we used genomic information to estimate inbreeding by detecting homozygous regions in the genomes of purebred Large White dams and Pietrain sires and their crossbred offspring. All individuals were genotyped using the IlluminaSNP60 porcine chip. As expected, fewer homozygous segments were detected in crossbr ed animals than in their parental populations. In addition, the total length of these segments was lower in crossbr ed animals. These observations can be interpreted as a decrease in consanguinity; however, the conservation of homozygous segments in crossbred offspring means that some haplotypes were shared between parental populations.
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https://hal.inrae.fr/hal-02737979
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Submitted on : Tuesday, June 2, 2020 - 8:07:31 PM
Last modification on : Wednesday, November 3, 2021 - 7:17:28 AM
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  • HAL Id : hal-02737979, version 1
  • PRODINRA : 493945

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Audrey Ganteil, Silvia Teresa Rodríguez-Ramilo, Bruno Ligonesche, Catherine Larzul. Diversité génomique de porcs issus d’un croisement Large-White x Piétrain. 52.Journées de la Recherche Porcine en France, Feb 2020, Paris, France. ⟨hal-02737979⟩

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