In our temperate regions, forests ecosystems developed on acidic soils are characterized by a low nutrient-content and an absence of fertilization. In this context, the life (plant, fungi, bacteria) is strongly dependent on the nutrients input coming from soil mineral weathering and atmospheric deposits. However, what do we know about the relative contribution of biotic and abiotic reactions on the mineral weathering process? What is the stability of soil mineral in time? Are there mineral weathering hot spots into the soil? Who are the actors involved in mineral weathering? Our present knowledge highlights that mineral dissolution is increased in the upper soil horizons where life is intense and the organic matter mineralised. Preliminary analyses also show that a large proportion of fine-size minerals evolves during the seasons in relation with the environmental conditions. Notably, the soil under the influence of the tree root systems (ie rhizosphere) appears as an important mineral weathering hot spot due to intense biological activities (root and associated microbes), which take place in.Despite its small size (ca. 1% of soil), it contributes up to half of the weathering flux. Recent results showed an enrichment of efficient mineral weathering bacteria in the rhizosphere, suggesting a functional complementation between the trees and their associated microbes. Future challenges will be to identify the abiotic and biotic parameters impacting weathering reactions, and to develop models integrating life. Multidisciplinary approaches combining isotopic and genetic toolsas well as biogeochemistry and ecology are needed