Skip to Main content Skip to Navigation
Journal articles

Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling

Abstract : Legume plants form a root-nodule symbiosis with rhizobia. This symbiosis establishment generally relies on rhizobium-produced Nod factors (NFs) and their perception by leguminous receptors (NFRs) that trigger nodulation. However, certain rhizobia hijack leguminous nodulation signalling via their type III secretion system, which functions in pathogenic bacteria to deliver effector proteins into host cells. Here, we report that rhizobia use pathogenic-like effectors to hijack legume nodulation signalling. The rhizobial effector Bel2-5 resembles the XopD effector of the plant pathogen Xanthomonas campestris and could induce nitrogen-fixing nodules on soybean nfr mutant. The soybean root transcriptome revealed that Bel2-5 induces expression of cytokinin-related genes, which are important for nodule organogenesis and represses ethylene- and defense-related genes that are deleterious to nodulation. Remarkably, Bel2-5 introduction into a strain unable to nodulate soybean mutant affected in NF perception conferred nodulation ability. Our findings show that rhizobia employ and have customized pathogenic effectors to promote leguminous nodulation signalling.
Document type :
Journal articles
Complete list of metadata
Contributor : Suzette Astruc Connect in order to contact the contributor
Submitted on : Wednesday, June 30, 2021 - 10:14:15 AM
Last modification on : Friday, August 5, 2022 - 10:57:16 AM


Publisher files allowed on an open archive


Distributed under a Creative Commons Attribution 4.0 International License



Safirah Tasa Nerves Ratu, Albin Teulet, Hiroki Miwa, Sachiko Masuda, Hien P Nguyen, et al.. Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling. Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-81598-6⟩. ⟨hal-03274463⟩



Record views


Files downloads