Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles (Review Article) The World Journal of Men's Health Year : 2021

Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training

Ashok Agarwal
Rakesh Sharma
Sajal Gupta
Renata Finelli
Neel Parekh
Neha Singh
  • Function : Author
Mahsa Darbandi
  • Function : Author
Paraskevi Vogiatzi
Ramadan Saleh
Hussein Kandil
Edmund Ko
Juan Alvarez
Marlon Martinez
Sunil Jindal
Gian Maria Busetto
Israel Maldonado
  • Function : Author
Christina Anagnostopoulou
Pallav Sengupta
Kambiz Gilany
  • Function : Author
Donald Evenson
  • Function : Author
Jaime Gosalvez
Rafael Ambar
  • Function : Author
Rupin Shah

Abstract

Semen analysis is the first, and frequently, the only step in the evaluation of male fertility. Although the laboratory procedures are conducted according to the World Health Organization (WHO) guidelines, semen analysis and especially sperm morphology assessment is very difficult to standardize and obtain reproducible results. This is mainly due to the highly subjective nature of their evaluation. ICSI is the choice of treatment when sperm morphology is severely abnormal (teratozoospermic). Hence, the standardization of laboratory protocols for sperm morphology evaluation represents a fundamental step to ensure reliable, accurate and consistent laboratory results that avoid misdiagnoses and inadequate treatment of the infertile patient. This article aims to promote standardized laboratory procedures for an accurate evaluation of sperm morphology, including the establishment of quality control and quality assurance policies. Additionally, the clinical importance of sperm morphology results in assisted reproductive outcomes is discussed, along with the clinical management of teratozoospermic patients.
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hal-03278904 , version 1 (01-06-2022)

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Ashok Agarwal, Rakesh Sharma, Sajal Gupta, Renata Finelli, Neel Parekh, et al.. Sperm Morphology Assessment in the Era of Intracytoplasmic Sperm Injection: Reliable Results Require Focus on Standardization, Quality Control, and Training. The World Journal of Men's Health, 2021, 39, ⟨10.5534/wjmh.210054⟩. ⟨hal-03278904⟩
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