Inter-species comparison of Milk Fat Globule Membrane proteins highlights the molecular diversity of lactadherin. - Archive ouverte HAL Access content directly
Journal Articles International Dairy Journal Year : 2012

Inter-species comparison of Milk Fat Globule Membrane proteins highlights the molecular diversity of lactadherin.

(1) , (1)
1

Abstract

Fat is present in milk as droplets of triacylglycerols surrounded by a complex membrane derived from the mammary epithelial cell called the milk fat globule membrane (MFGM). In-depth proteomic studies have been published for bovine MFGM proteins. However, to date, only sparse studies exist on MFGM proteins from non-cow milk. We have therefore characterized MFGM proteins in goat, sheep, horse and camel milk and we have highlighted prominent differences across species, especially for lactadherin, a major protein of the milk fat globule membrane. Indeed, lactadherin from goat and sheep milk appears as a single polypeptide chain in 10% sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE), whereas two and four polypeptide chains are respectively identified for lactadherin from camel and horse milk. Implications of the findings, especially with regard to bioactive properties of milk are discussed.

Dates and versions

hal-03805538 , version 1 (07-10-2022)

Identifiers

Cite

Christelle Cebo, Patrice Martin. Inter-species comparison of Milk Fat Globule Membrane proteins highlights the molecular diversity of lactadherin.. International Dairy Journal, 2012, ⟨10.1016/j.idairyj.2011.09.017⟩. ⟨hal-03805538⟩
7 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More