Newly developed plant-based foods can vary in protein, but can consumers detect these differences? Here, we sought to explore whether repeated consumption of a novel plant-based protein-containing food impacts the macronutrient profile of other foods in the diet. Healthy adult meat-eating participants consumed a portion of a novel plant-based test food daily over 5 days. In a between-group design, two levels of protein, 10% and 25%, were tested. Participants kept a digital food diary and attended an experimental session on day 1 and day 8. During the experimental sessions, participants ate the test food (preload), followed by an ad libitum buffet. They also evaluated their liking for the test food, alone or in combination with protein or carbohydrates, together with its expected satiety. Thirty-eight (n(25%)=20) participants completed the intervention. The higher (25%) protein test food received lower liking and higher expected satiety ratings (p<0.05). Both groups declared a greater desire to eat the test food in combination with carbohydrates than with protein (p<0.001). There were no between-group differences in macronutrient intake at the buffet, but the 25% group increased their lipid and calorie intake by 14% between sessions (p<0.05). Food diaries show an 20% reduction in daily protein intake in the 25% group over 5 days (p=0.04). In this study, participants used test foods as protein sources independently of their protein content. However, after several days of intervention, the higher-protein group reduced its daily protein intake indicating a potential compensation on physiological level.