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Journal Articles Respiratory Medicine and Research Year : 2023

Pulmonary adverse events of breast silicone implants and silicone injection


The incidence of breast implants and silicone injections has continuously increased since their FDA approval for use in the 19600s. The prevalence of overall adverse events is approximately 20%. The actual incidence of pulmonary adverse events is unknown. This review focuses on the pulmonary adverse events of breast implants and silicone injections. Vascular complications are represented by acute and chronic embolisation syndromes with a clinico-radiological presentation of alveolar hemorrhage. Inflammatory complications are numerous, including siliconoma, which is a granulomatous reaction mimicking a mesothelioma. On the other hand, there are some reports arguing a link between the development of auto-immune diseases and breast implants, such as scleroderma, rheumatoid arthritis, Sjoeurogren's syndrome, and dermatomyositis. Finally, for patients with asthma, breast implants may contribute to poor disease control. Cases of eosinophilic granulomatosis with polyangeitis have been described. Thus, it is of interest to decipherate mechanisms and incidence of these effects in prospective studies to better manage pulmonary diseases in patients wearing breast implants in order to understand their role as culprits or bystanders. In addition, characterization of subpopulations with increased risk of adverse events is needed as we highlighted that some subpopulations seem to be at greater risk of developing them, notably asthmatics.
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Dates and versions

hal-04532946 , version 1 (04-04-2024)



Eléonore Simon, Laurie Pahus, Pascal Chanez. Pulmonary adverse events of breast silicone implants and silicone injection. Respiratory Medicine and Research, 2023, 84, pp.101065. ⟨10.1016/j.resmer.2023.101065⟩. ⟨hal-04532946⟩
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