Worldwide, parasitic infections with gastro intestinal nematodes (GINs) remain a major threat on outdoors breeding of small ruminants, affecting goat and sheep’s health, welfare and production, consequence for the breeders. Until recently, the control of these parasitic infections has relied mainly on the repeated use of commercial synthetic anthelmintic (AH) treatments. However, nowadays, the constant and widespread use of such chemical AH molecules is facing several limits, in particular the development and diffusion of AH resistances in GINs populations. Bioactive plants with AH properties represent one of the current potential alternative and/or complementary solutions to the synthetic AH which have been extensively studied. Within this framework of studies, forage Legumes containing condensed tannins are a main model of bioactive plants and related plant secondary metabolites to explore the 2 concepts of the integrated, sustainable control of parasitic GIN and of nutraceuticals. This review aims at addressing 4 specific issues :1) to explain the concepts of integrated control of NGIs and nutraceuticals, 2) to sum up the main anti parasitic effects of CT containing plants, 3) to highlight the relations between basic and applied researches and possible developments in small ruminants’ farming and 4) to illustrate the possible connections between researches in Veterinary and Medical Sciences within the ‘One World; one Health” framework.