Anaerobic digestion (AD) of organic waste from agriculture and others sectors is a widely used technology which shows increasing implementation due to its capacity to produce renewable energy and also to reduce greenhouse gas emissions from waste management. The development of AD is also an opportunity to improve nutrient recycling from organic waste through the development of an eco-efficient post-treatment system. In this context, LCA was applied to evaluate the sustainability of different raw digestate post-treatment technologies regarding recycling of nutrients from agricultural and organic waste to agricultural soils for decreased resource depletion and climate mitigation. Substitution of the use of N and P mineral fertilizers with recycled soil health improver or organic fertilizers products as function of five different post-treatment technologies and raw digestate characteristics was evaluated. A particular attention was carried to (1) the gaseous emissions (NH3 and N2O) from process (post-treatment) but also after land spreading and (2) the carbon cycle considering the CO2 carbon costs of fertiliser production and the soil carbon sequestration benefit.