Clones of cells switch from reduction to enhancement of size variability in Arabidopsis sepals - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Development (Cambridge, England) Year : 2017

Clones of cells switch from reduction to enhancement of size variability in Arabidopsis sepals

Abstract

Organs form with remarkably consistent sizes and shapes during development, whereas a high variability in growth is observed at the cell level. Given this contrast, it is unclear how such consistency in organ scale can emerge from cellular behavior. Here, we examine an intermediate scale, the growth of clones of cells in Arabidopsis sepals. Each clone consists of the progeny of a single progenitor cell. At early stages, we find that clones derived from a small progenitor cell grow faster than those derived from a large progenitor cell. This results in a reduction in clone size variability, a phenomenon we refer to as size uniformization. By contrast, at later stages of clone growth, clones change their growth pattern to enhance size variability, when clones derived from larger progenitor cells grow faster than those derived from smaller progenitor cells. Finally, we find that, at early stages, fast growing clones exhibit greater cell growth heterogeneity. Thus, cellular variability in growth might contribute to a decrease in the variability of clones throughout the sepal.
Fichier principal
Vignette du fichier
2017_Tsugawa_Develop_1.pdf (3.25 Mo) Télécharger le fichier
Origin : Publisher files allowed on an open archive
Loading...

Dates and versions

hal-02619420 , version 1 (25-05-2020)

Licence

Attribution

Identifiers

Cite

Satoru Tsugawa, Nathan Hervieux, Daniel Kierzkowski, Anne-Lise Routier-Kierzkowska, Aleksandra Sapala, et al.. Clones of cells switch from reduction to enhancement of size variability in Arabidopsis sepals. Development (Cambridge, England), 2017, 144 (23), pp.4398-4405. ⟨10.1242/dev.153999⟩. ⟨hal-02619420⟩
17 View
51 Download

Altmetric

Share

Gmail Facebook X LinkedIn More