Direct Access to Fluorinated Thiadiazolo[3,2-a]pyrimidin-7-one Systems
Résumé
A mild, simple method for the regioselective synthesis of thiadiazolo[3,2-a]pyrimidin-7-ones bearing a perfluoroalkyl group is reported. In order to study the core reactivity, various nucleophile substitutions were performed involving the reactive carbon-bromide bond via a one-pot strategy.