Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception? - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Journal of Theoretical Biology Year : 2008

Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception?

Abstract

In response to the need to efficiently control mammal pest populations while avoiding unnecessary suffering, applied and theoretical ecologists have recently focused on virus-vectored immunocontraception (VVIC). So far, modellers have only considered a non-sexual approach (models of sexually reproducing populations without explicitly discerning between the sexes), which appears dubious in view of the sex-specificity of VVIC agents. In this paper, we derive and compare predictions of non-sexual and two-sex models of the spread of a VVIC agent in a host population in order to assess the adequacy of non-sexual models in this context. Our results show that predictions of non-sexual and two-sex models generally diverge and that non-sexual models often fail to predict the control impact of VVIC. We thus recommend using two-sex models, especially if the mating system and life history of the target species are known. Our analysis also shows that female-specific viruses generally give better results than male-specific ones, and suggests that virus choice should focus more on its sterilizing power rather than transmission efficiency. (c) 2007 Elsevier Ltd. All rights reserved.
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hal-02665551 , version 1 (31-05-2020)

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Anne Deredec, Luděk Berec, David S. Boukal, Franck Courchamp. Are non-sexual models appropriate for predicting the impact of virus-vectored immunocontraception?. Journal of Theoretical Biology, 2008, 250 (2), pp.281-290. ⟨10.1016/j.jtbi.2007.09.037⟩. ⟨hal-02665551⟩
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