Anaerobiosis and low specific growth rates enhance hemolysin BL production by Bacillus cereus F4430/73 - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Archives of Microbiology Year : 2004

Anaerobiosis and low specific growth rates enhance hemolysin BL production by Bacillus cereus F4430/73

Abstract

Bacillus cereus F4430/73 produced the highest levels of hemolysin BL (HBL) when grown under anaerobiosis in MOD medium. Anaerobic cells grown in a chemostat at low specific growth rate (0.1–0.2 h–1) expressed up to sevenfold more HBL than did cells held at a faster growth rate. At 0.2 h–1, the presence of 90 mM glucose resulted in inhibition of HBL production. Glucose was found to repress HBL induction at the mRNA level, indicating the potential involvement of catabolite repression in the regulation of HBL. Based on these data, it is suggested that growth rate could be an effector of catabolite regulation of HBL.

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hal-02681797 , version 1 (31-05-2020)

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Catherine Duport, S. Thomassin, G. Bourel, P. Schmitt. Anaerobiosis and low specific growth rates enhance hemolysin BL production by Bacillus cereus F4430/73. Archives of Microbiology, 2004, 182 (1), pp.90-95. ⟨10.1007/s00203-004-0688-y⟩. ⟨hal-02681797⟩
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