CAR(H)(T)AGene: multipopulation integrated genetic and radiation hybrid mapping
Résumé
CarthaGene: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. CarthaGene: performs multipoint maximum likelihood estimations with accelerated expectation– maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. Carth aGene: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.