Marker assisted recurrent selection for cumulating additive and interactive QTL in recombinant inbred lines - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles TAG Theoretical and Applied Genetics Year : 1999

Marker assisted recurrent selection for cumulating additive and interactive QTL in recombinant inbred lines

Abstract

A computer program has been designed to manage marker information in recombinant inbred-line populations. The objective is to select pairs of inbred lines (either recombinant-inbred or doubled-haploid) to be intercrossed, in order to accumulate all or most favourable alleles, either with additive effects or with interactive effects. The population size required to have a 95% chance of obtaining the best line from a given cross is computed, taking into account the number of QTLs and the probability that no recombination event occurs in any of the QTL confidence intervals. It is shown that the accuracy of QTL location greatly affects selection efficiency and that a recurrent selection scheme is highly preferable for pyramiding many QTLs. An application to the bread-making quality improvement of wheat is presented.

Dates and versions

hal-02694019 , version 1 (01-06-2020)

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Gilles Charmet, Nathalie Robert, Marie-Reine Perretant, Georges G. Gay, Pierre Sourdille, et al.. Marker assisted recurrent selection for cumulating additive and interactive QTL in recombinant inbred lines. TAG Theoretical and Applied Genetics, 1999, 99 (7-8), pp.1143-1148. ⟨10.1007/s001220051318⟩. ⟨hal-02694019⟩
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