The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Journal Articles Cell Growth and Differentiation Year : 1994

The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins

Abstract

We have characterized a new human gene, named GARP, localized in the 11q14 chromosomal region. GARP comprises two coding exons, is expressed as two major transcripts of 4.4 and 2.8 kilobases, respectively, and encodes a putative transmembrane protein of 662 amino acids, the extracellular portion of which is almost entirely made of leucine-rich repeats. The molecular weight of the protein immunoprecipitated from transfected cells is 80,000. The GARP protein has structural similarities with the human GP Ib alpha and GP V platelet proteins, and with the Chaoptin, Toll, and Connectin adhesion molecules of Drosophila.
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Dates and versions

hal-02711879 , version 1 (01-06-2020)

Identifiers

  • HAL Id : hal-02711879 , version 1
  • PRODINRA : 441921
  • PUBMED : 8180135
  • WOS : A1994MW52500013

Cite

Vincent Ollendorff, Tetsuro Noguchi, Odile Delapeyrière, Daniel Birnbaum. The GARP gene encodes a new member of the family of leucine-rich repeat-containing proteins. Cell Growth and Differentiation, 1994, 5 (2), pp.213-219. ⟨hal-02711879⟩

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