Colonization of the muscle extracellular matrix components by enterohemorrhagic escherichia coli
Résumé
Enterohemorrhagic Escherichia coli (EHEC) are anthropozoonotic agents responsible for repeated food-poisoning cases often caused by contaminated burgers. EHEC are Shiga-toxin producing E. coli (STEC) responsible for foodborne poisoning mainly incriminated to the consumption of contaminated beef meat. Eight serogroups are especially of high-risk for human health, i.e. O157, O26, O45, O103, O111, O121, O145 and O104. Ruminants are the main natural reservoir for EHEC and primary bacterial contamination occurs at the dehiding stage of slaughtering. The extracellular matrix (ECM) is the most exposed part of the skeletal muscles in beef carcasses. Investigating bacterial colonization to the skeletal-muscle extracellular matrix (ECM) proteins, it appeared that environmental factors influenced specific and non-specific bacterial adhesion of O157 and non-O157 EHEC as well as biofilm formation. From this first comprehensive investigation of EHEC adhesion to ECM proteins with respect to muscle biology and meat processing, new research directions for the development of innovative practices to minimize the risk of meat contamination are further discussed.
Domaines
Microbiologie et Parasitologie
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