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T047 Ultrasonic circular cyclo coagulation in patients with primary open-angle glaucoma: a multicenter clinical trial: Session 1 Epidemiology, immunopathology, and the role of cytokines in non-infectious uveitis

Abstract : Purpose To evaluate the efficacy and safety of the Ultrasonic Circular Cyclo Coagulation (UC3) procedure in patients with primary open-angle glaucoma (POAG). Methods Prospective multicenter clinical trial. 42 eyes of 42 patients with POAG, intraocular pressure (IOP) > 21 mmHg, an average of 1.65 failed previous surgeries and an average of 3.2 hypotensive medications were insonified with a probe comprising 6 piezoelectric transducers. 18 patients (group 1) were treated with a 4 seconds exposure time for each shot and 24 patients (group 2) with a 6 seconds exposure time. Follow-up visits were performed at 1 day, 1 week, 1, 2, 3, 6 and 12 months after. Results IOP was significantly reduced in both groups (p<0.05), from a mean preoperative value of 28.6 ± 4.7 mmHg in group 1 and 28.1 ± 8.6 mmHg in group 2 to a mean value of 16.1 ± 2.8 mmHg in group 1 and 16.7 ± 4.4 mmHg in group 2 at last follow-up. Success (IOP reduction >20%) was achieved in 12 of 18 (67%) eyes of the group 1 and in 17 of 24 (71%) eyes of the group 2. Four patients were re-treated. No major intra- or post-operative complications occurred. Conclusion UC3 seems to be an effective and well-tolerated method to reduce intraocular pressure in patients with POAG.
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https://hal.inrae.fr/hal-02808254
Déposant : Migration Prodinra <>
Soumis le : samedi 6 juin 2020 - 05:03:32
Dernière modification le : vendredi 12 juin 2020 - 10:43:26

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  • HAL Id : hal-02808254, version 1
  • PRODINRA : 367799

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Florent Aptel, Philippe Denis, Jean-Francois Rouland, Jean-Philippe Nordmann, Yves M. Lachkar, et al.. T047 Ultrasonic circular cyclo coagulation in patients with primary open-angle glaucoma: a multicenter clinical trial: Session 1 Epidemiology, immunopathology, and the role of cytokines in non-infectious uveitis. European Association for Vision and Eye Research (EVER) Congress, Sep 2013, Nice, France. 54, Association for Research in Vision and Ophthalmology, 284 p., 2013, Investigative Ophthalmology and Visual Science. ⟨hal-02808254⟩

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