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Fast-Growing Alveolar Echinococcosis Following Lung Transplantation

Abstract : Alveolar echinococcosis is a rare but life-threatening infection caused by the parasiteEchinococcus multilocularis. Its natural history is characterized by a slow parasitic growth over several years. Increased incidence and shorter development delay have been reported in immune-compromised patients. We report the reactivation of aborted lesions within 12 months of lung transplantation leading to a fast-growing aggressive hepatic lesion. Timely identification of alveolar echninococcosis allowed prompt albendazole treatment and radical surgery leading to a favorable outcome 42 months after transplantation. However, close clinical, serological and radiological monitoring is required to rule out relapses in the long term. The pre-existence of aborted self-limited lesions of alveolar echinococcosis and the possibility for their atypical rapid growth in patients undergoing profound immunosuppression should be known by healthcare providers, even if working in non-endemic areas.
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https://hal.inrae.fr/hal-03154574
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Submitted on : Monday, June 7, 2021 - 4:02:37 PM
Last modification on : Friday, June 11, 2021 - 3:26:40 PM

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Clarisse Dupont, Frédéric Grenouillet, Jean-Yves Mabrut, Frédérique Gay, Florence Persat, et al.. Fast-Growing Alveolar Echinococcosis Following Lung Transplantation. Pathogens, MDPI, 2020, 9 (9), pp.756. ⟨10.3390/pathogens9090756⟩. ⟨hal-03154574⟩

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