Skip to Main content Skip to Navigation
Journal articles

Fermentation of Ferulated Arabinoxylan Recovered from the Maize Bioethanol Industry

Abstract : Maize by-product from the bioethanol industry (distiller’s dried grains with solubles, DDGS) is a source of ferulated arabinoxylan (AX), which is a health-promoting polysaccharide. In the present study, AX from DDGS was fermented by a representative colonic bacterial mixture (Bifidobacterium longum, Bifidobacterium adolescentis, and Bacteroides ovatus), and the effect of the fermented AX (AX-f) on the proliferation of the cell line Caco-2 was investigated. AX was efficiently metabolized by these bacteria, as evidenced by a decrease in the polysaccharide molecular weight from 209 kDa to < 50 kDa in AX-f, the release of ferulic acid (FA) from polysaccharide chains (1.14 µg/mg AX-f), and the short-chain fatty acids (SCFA) production (277 µmol/50 mg AX). AX-f inhibited the proliferation of Caco-2 cells by 80–40% using concentrations from 125–1000 µg/mL. This dose-dependent inverse effect was attributed to the increased viscosity of the media due to the polysaccharide concentration. The results suggest that the AX-f dose range and the SCFA and free FA production are key determinants of antiproliferative activity. Using the same polysaccharide concentrations, non-fermented AX only inhibited the Caco-2 cells proliferation by 8%. These findings highlight the potential of AX recovered from the maize bioethanol industry as an antiproliferative agent once fermented by colonic bacteria
Complete list of metadata

https://hal.inrae.fr/hal-03251277
Contributor : Dominique Fournier <>
Submitted on : Sunday, June 6, 2021 - 10:12:38 PM
Last modification on : Monday, June 7, 2021 - 3:36:50 AM

File

Mendez-Encinas-Processes-2021-...
Publisher files allowed on an open archive

Licence


Distributed under a Creative Commons Attribution 4.0 International License

Identifiers

Citation

Mayra Mendez-Encinas, Dora Valencia-Rivera, Elizabeth Carvajal-Millan, Humberto Astiazaran-Garcia, Valérie Micard, et al.. Fermentation of Ferulated Arabinoxylan Recovered from the Maize Bioethanol Industry. Processes, MDPI, 2021, 9 (1), pp.165. ⟨10.3390/pr9010165⟩. ⟨hal-03251277⟩

Share

Metrics

Record views

67

Files downloads

26