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Multi-omics Approach Reveals How Yeast Extract Peptides Shape Streptococcus thermophilus Metabolism

Abstract : Improving the performance and industrial robustness of bacteria used in fermentations and food industry remains a challenge. We showed here that two Streptococcus thermophilus fermentations, performed with the same strain in media that differ only by their yeast extract compositions and, more especially, their peptide contents, led to similar growth kinetics and final biomasses, but several genes and proteins were differentially expressed/produced. In other words, subtle variations in peptide composition of the growth medium can finely tune the metabolism status of the starter. Our work, therefore, suggests that acting on growth medium components and especially on their peptide content, we could modulate bacterial metabolism and produce bacteria differently programmed for further purposes. This might have applications for preparing active starter cultures.
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https://hal.inrae.fr/hal-03342053
Contributor : Roselyne Tâche <>
Submitted on : Monday, September 13, 2021 - 10:41:23 AM
Last modification on : Monday, September 20, 2021 - 4:55:55 PM

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Lucas Proust, Eloi Haudebourg, Alain Sourabié, Martin Pedersen, Iris Besançon, et al.. Multi-omics Approach Reveals How Yeast Extract Peptides Shape Streptococcus thermophilus Metabolism. Applied and Environmental Microbiology, American Society for Microbiology, 2020, 86 (22), ⟨10.1128/AEM.01446-20⟩. ⟨hal-03342053⟩

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