Botrytis cinerea causes one of the most serious diseases in grapevines, namely Botrytis Bunch Rot (BBR). This pathogen can reduce drastically both yield and quality of wine. To control the disease, pesticides have long been used, generating harms to human health and to the environment. Thus, new control strategies allowing to reduce application of chemical products need to be developed, considering the main principles of Integrated Pest Management (IPM). A classification of different grape cvs. according to their susceptibility to B. cinerea is an essential management indicator in IPM. Although such classifications are available in the literature, they are based mostly on professional experience rather than experimental data and few studies compared different cultivars under the same environmental and management conditions. Furthermore, no study compares cultivar classification in contrasting climatic and cultural conditions. Thus, to classify and compare the susceptibility to the pathogen between different wine grape cvs., a study was carried out in Chile (Maule region) and France (Bordeaux area) including 13 common cvs. field trials, under natural inoculum pressure, were carried out between 2011 and 2015, during 2 and 3 seasons in Chile and France, respectively. The fruit maturity and cluster compactness were measured and/or simulated in order to relate these factors to the resulting susceptibility ranking. The results showed that cultivar classification was similar in both countries, despite the contrasting climatic conditions and cultural practices. Sauvignon Blanc and Gewürztraminer were the highest susceptible cvs., whereas Petit Verdot, Cabernet Sauvignon, Mourvèdre and Syrah were rather resistant. These results are in accordance to previous ones in literature. However, for the other cvs. evaluated, their ranking differed to some extent from the literature. Fruit maturity and cluster compactness, depending significantly on the cultivar, proved to be very important factors governing susceptibility to B. cinerea. The susceptibility classification of cultivars remains a key parameter in decision support systems and then, both variables cluster compactness and fruit maturity could be used to support this classification. Further investigation should be conducted to better understand the relationships between susceptibility to B. cinerea and other variables (e.g. clone, vigor, rootstock), in order to develop new IPM strategies.