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Article Dans Une Revue Journal of Pediatric Gastroenterology and Nutrition Année : 2021

Drugs in Focus: Octreotide Use in Children With Gastrointestinal Disorders

Résumé

Octreotide, a somatostatin analogue, has been used for more than 20 years in children with gastrointestinal bleeding, chylothorax or chylous ascites, intestinal lymphangiectasia, pancreatitis, intestinal dysmotility, and severe diarrhoea; however, until now, there is a lack of randomised clinical trials evaluating the efficacy of this compound in childhood. Hence, we aimed to review the literature in order to determine the evidence of its use and safety in children, using PubMed from 2000 to 2021 with the search terms "octreotide" and "children" and "bleeding or chylous ascites or chylothorax or acute pancreatitis or lymphangiectasia or diarrhoea or intestinal dysmotility".

Dates et versions

hal-03513901 , version 1 (06-01-2022)

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Emmanuel Mas, Osvaldo Borrelli, Ilse Broekaert, J. Martin De-Carpi, Jernej Dolinsek, et al.. Drugs in Focus: Octreotide Use in Children With Gastrointestinal Disorders. Journal of Pediatric Gastroenterology and Nutrition, 2021, 74 (1), pp.1-6. ⟨10.1097/MPG.0000000000003294⟩. ⟨hal-03513901⟩
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