Interest in exploring new and exotic types of berries has grown in recent years. Highly valued for its unique flavor, texture and color, recent researches have shown that Andean berries are an important source of bioactive compounds. This article provides botanical and agronomic descriptions and reviews the chemical and biological activities of two types of berries (Physalis peruviana L. and Solanum betaceum C.) and one commonly known as a berry, Rubus glaucus B. All highly consumed in Ecuador and enjoying great popularity in Andean traditional medicine. Although both traditional folk medicine and composition of these berries suggest significant health benefits, few studies to date have investigated these potentials.