Recent and potentially ongoing invasion of lepidopteran genomes by a helitron
Résumé
A large part of eukaryotic genomes is composed of inactivated mobile elements (TEs for
Transposable Elements), corresponding to remnants of ancient waves of TE invasions. TEs also
play a very important role in adaptation to new ecological conditions. The most famous example
is the industrial melanism of the peppered moth: the black color has been shown to result from
the insertion of a transposon within a gene. Considerable progress in sequencing approaches
now makes it possible to assemble TE-rich regions within genomes. We found that a TE of the
helitron type secreted in the genital fluid of a parasitoid wasp is present as identical copies in
the genome of 5 Lepidopteran species sequenced by the Darwinian tree of life project from
specimens collected in UK, suggesting a recent wave of introduction of this TE in Lepidoptera.
We hypothesize that increase of parasitoid introductions worldwide could, as for viral infections,
increase the rate of TE invasions, and play a role in populations decline. We recently amplified
the helitron from specimens collected in France indicating that the spread of this TE is not
limited to UK. We will map the extent of the invasion in the geographical range of the species
Pararge aegeria and Polyommatus icarus, in particular in areas where these species have been
recently introduced such as Madeira island (P. aegeria) and Québec (P. icarus) since founders
of the current populations could have been introduced before helitron spread, thus allowing an
approximate dating of the epidemic.