Quantitative brainstem and spinal MRI in amyotrophic lateral sclerosis: implications for predicting noninvasive ventilation needs - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
Article Dans Une Revue Journal of Neurology Année : 2024

Quantitative brainstem and spinal MRI in amyotrophic lateral sclerosis: implications for predicting noninvasive ventilation needs

M. Khamaysa

Résumé

Respiratory complications resulting from motor neurons degeneration are the primary cause of death in amyotrophic lateral sclerosis (ALS). Predicting the need for non-invasive ventilation (NIV) in ALS is important for advance care planning and clinical trial design. The aim of this study was to assess the potential of quantitative MRI at the brainstem and spinal cord levels to predict the need for NIV during the first six months after diagnosis.
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Dates et versions

hal-04328762 , version 1 (07-12-2023)

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M. Khamaysa, M. Lefort, Mélanie Pélégrini-Issac, Alexandra Lackmy-Vallée, A. Preuilh, et al.. Quantitative brainstem and spinal MRI in amyotrophic lateral sclerosis: implications for predicting noninvasive ventilation needs. Journal of Neurology, 2024, 271 (3), pp.1235-1246. ⟨10.1007/s00415-023-12045-x⟩. ⟨hal-04328762⟩
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