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Journal Articles The World Journal of Men's Health Year : 2024

Male Infertility: New Developments, Current Challenges, and Future Directions

Murat Gül
Hussein Kandil
Ramadan Saleh
Eric Chung
Parviz Kavoussi
Taymour Mostafa
Rupin Shah
Ashok Agarwal


There have been many significant scientific advances in the diagnostics and treatment modalities in the field of male infertility in recent decades. Examples of these include assisted reproductive technologies, sperm selection techniques for intracytoplasmic sperm injection, surgical procedures for sperm retrieval, and novel tests of sperm function. However, there is certainly a need for new developments in this field. In this review, we discuss advances in the management of male infertility, such as seminal oxidative stress testing, sperm DNA fragmentation testing, genetic and epigenetic tests, genetic manipulations, artificial intelligence, personalized medicine, and telemedicine. The role of the reproductive urologist will continue to expand in future years to address different topzics related to diverse questions and controversies of pathophysiology, diagnosis, and therapy of male infertility, training researchers and physicians in medical and scientific research in reproductive urology/andrology, and further development of andrology as an independent specialty.
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Dates and versions

hal-04383326 , version 1 (09-01-2024)



Murat Gül, Giorgio Ivan Russo, Hussein Kandil, Florence Boitrelle, Ramadan Saleh, et al.. Male Infertility: New Developments, Current Challenges, and Future Directions. The World Journal of Men's Health, 2024, 42, ⟨10.5534/wjmh.230232⟩. ⟨hal-04383326⟩
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