797. Genetic relationships among immune response traits of young healthy pigs evaluated by immunoassays
Résumé
This study estimates phenotypic and genetic correlations of different components of the immune system of young healthy pigs, evaluated by various immunoassays, with an aim towards revealing a deeper understanding of the immune system of pigs and the role of immunoassays in predicting disease resilience. The composition of circulating immune cells, their phagocytic activity, and immune response measured by the High Immune Response (HIR™) technology were found to be heritable. The percentages of granulocytes and neutrophils in blood had high positive phenotypic and genetic correlations with each other and with the percentage of cells that showed phagocytosis activity. The HIR tests showed antibody-mediated immune response to be positively genetically correlated with cell composition traits, while cell-mediated immune response had a positive genetic correlation with only % eosinophils. These results suggest that immunoassays conducted on young healthy pigs provide important genetic information on their immune response profiles.