SEARCH FOR NEW MUTATIONS IN CATTLE BY SYSTEMATIC WHOLE GENOME RESEQUENCING
Abstract
Systematic whole genome sequencing of artificial insemination bulls
presents strong advantages:
• Discovery of all genetic variants, including the rarest ones
• Improvement of imputation up to the sequence level, especially in
medium size populations
• Identification of candidate variants of QTL
• Early identification of new potential genetic defects and their
carriers before wide spreading in the population
As part of the SeqOccIn project, 571 AI bulls from 14 dairy and beef
breeds were sequenced (Illumina NovaSeq technology). We present
the strategy used to reduce false positives, with some of the results
Domains
Life Sciences [q-bio]| Origin | Files produced by the author(s) |
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