Article Dans Une Revue British Journal of Dermatology Année : 2025

The Tryptophan-Serotonin Axis in Albinism: an interesting lead?

Résumé

Serotonin and other tryptophan-derived metabolites are altered in patients with albinism, with a distinct shift toward the serotonin pathway and impaired serotonin degradation. These metabolic disturbances suggest a potential link between tryptophan metabolism and pigmentation defects. Tryptophan profiling may offer novel diagnostic or therapeutic avenues for albinism.

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hal-05238279 , version 1 (03-09-2025)

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Benoît Gendrot, Marion Falabregue, Camille Huet, Stéphanie Matar, Bénédicte Oules, et al.. The Tryptophan-Serotonin Axis in Albinism: an interesting lead?. British Journal of Dermatology, 2025, ⟨10.1093/bjd/ljaf333⟩. ⟨hal-05238279⟩
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