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Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism.

Abstract : In mammals, the Tribbles family includes widely expressed serine-threonine kinase-like proteins (TRIB1, TRIB2 and TRIB3) that are involved in multiple biological processes including cell proliferation and fatty acid (FA) metabolism. Our recent studies highlighted the importance of FA metabolism in cumulus cells (CC) during oocyte maturation in vertebrates and reported a higher TRIB1 expression in CC surrounding in vivo mature oocytes as compared to immature ooocytes in mice and cows. The objective was to investigate Tribbles expression patterns in bovine CC during in vitro maturation (IVM) and to examine their roles in the cumulus-oocyte complex.
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https://hal.archives-ouvertes.fr/hal-00995701
Contributor : Franck Chesnel Connect in order to contact the contributor
Submitted on : Friday, May 23, 2014 - 4:03:52 PM
Last modification on : Friday, May 6, 2022 - 2:22:08 PM

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Daphné Brisard, Franck Chesnel, Sébastien Elis, A. Desmarchais, L. Sanchez-Lazo, et al.. Tribbles expression in cumulus cells is related to oocyte maturation and fatty acid metabolism.. Journal of Ovarian Research, 2014, 7 (1), pp.44. ⟨10.1186/1757-2215-7-44⟩. ⟨hal-00995701⟩

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