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FrameDP: sensitive peptide detection on noisy matured sequences

Abstract : Transcriptome sequencing represents a fundamental source of information for genome-wide studies and transcriptome analysis and will become increasingly important for expression analysis as new sequencing technologies takes over array technology. The identification of the protein-coding region in transcript sequences is a prerequisite for systematic amino acid-level analysis and more specifically for domain identification. In this article, we present FrameDP, a self-training integrative pipeline for predicting CDS in transcripts which can adapt itself to different levels of sequence qualities.
Keywords : FrameDP
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Jerome Gouzy, Sebastien Carrere, Thomas Schiex. FrameDP: sensitive peptide detection on noisy matured sequences. Bioinformatics, Oxford University Press (OUP), 2009, 25 (5), pp.670-671. ⟨10.1093/bioinformatics/btp024⟩. ⟨hal-02665259⟩



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