Recent advances in portability of analytical equipment have been considered to enlighten the advantages offered by portable instrumentation on greening the analytical methods. Their use drastically reduces sampling, sample stockage, and transport, thus avoiding environmental side effects and risks, also improving decision-making. The fact that portable instrumentation is, in general, less expensive than bench instruments and apparatuses makes also available the analytical tools for extended sectors of the population, thus making accessible the advantages derived from analytical methods. The role of sensor technology and portable miniaturized systems has been considered to be paid special attention to the portable sample treatment systems based on microwave and ultrasound technologies and the use of image processing systems.