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Exposition aux gaz d’échappement diesel durant la gestation : quelles conséquences sur le développement foeto-placentaire ? Apport des modèles animaux

Abstract : Air pollution is a major threat for human health, causing 3.7 million premature deaths in 2012 world- wide. Elderly people, children and people suffering from asthma in outbursts of air pollution peaks are the most concerned whereas pregnant women are most often neglected. Epidemiological surveys and studies using animal models indicate that the components of air pollution can disturb placental function, reduce foetal growth and induce oxidative stress and inflammation in the mother, placenta and foetus. On the long term, these effects can contribute to the current worldwide increase in adult metabolic diseases in the context of the Developmental Origins of Health and Disease (DOHaD). It is therefore important to include pregnant women as recipients of preventative messages for air pol- lution and to carry on research on long term effects using relevant animal models and procedures.
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https://hal.inrae.fr/hal-02630765
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Submitted on : Wednesday, May 27, 2020 - 6:21:14 AM
Last modification on : Tuesday, August 24, 2021 - 9:08:04 AM

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Sarah Valentino, Anne Couturier-Tarrade, Pascale Chavatte-Palmer. Exposition aux gaz d’échappement diesel durant la gestation : quelles conséquences sur le développement foeto-placentaire ? Apport des modèles animaux. Bulletin de l'Académie Vétérinaire de France, Académie vétérinaire de France, 2016, 169 (3), pp.1-10. ⟨10.4267/2042/61628⟩. ⟨hal-02630765⟩

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