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Proteomic profile evolution during steatosis development in ducks

Abstract : We investigated a protein profile evolution during steatosis in ducks using 2-dimensional electrophoresis gels to better understand the mechanisms underlying liver steatosis at the level of hepatic proteins in waterfowl. Two-dimensional electrophoresis gels were performed in the liver at different stages of steatosis in the duck. Mule ducks were slaughtered after 0, 14, or 23 meals of overfeeding, according to commercial conditions. Thirty-one proteic spots were differentially expressed between 3 or 2 durations of overfeeding: 3 spots were differentially expressed between the 3 times and 28 spots were differentially expressed between 2 times. The identified proteins (14) could be regrouped into 5 categories: enzymes, translation factors, proteins involved in cell structure, proteins with antioxidant properties, and proteins that can link calcium. This study opens new research areas in the understanding of steatosis in waterfowl, such as cell structure and oxidative stress.
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https://hal.inrae.fr/hal-02649626
Déposant : Migration Prodinra <>
Soumis le : vendredi 29 mai 2020 - 12:23:10
Dernière modification le : mardi 25 août 2020 - 11:30:05

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Marie-Laure Bax, Christophe Chambon, Nathalie Marty-Gasset, Herve Remignon, Xavier Fernandez, et al.. Proteomic profile evolution during steatosis development in ducks. Poultry Science, Poultry Science Association, 2012, 91 (1), pp.112-120. ⟨10.3382/ps.2011-01663⟩. ⟨hal-02649626⟩

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