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Poster communications

High or low cytosolyc NAD(P) during partthenogenetic activation does not induce aberrant centriole formation in the mouse

Abstract : The increase in egg metabolism triggered by fertilization initiates the meiotic exit and participates in organizing the maternal and paternal centrosomes of the first mitotic spindle. In the mouse, unfertilized oocytes have all constituents needed to organize a bipolar mitotic apparatus but we don't know whether changes in the reducing power of the NAD(P)H co-factor induced by parthenogenetic agents can generate aberrant centriole distribution in parthenogenetic cell lines. In the present experiment, we activated freshly ovulated mouse eggs by a series of Ca2+ signals either in the presence of lactate which is a high cytosolic reducing agent or, in the presence of pyruvate which is a high cytosolic oxidant.
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Poster communications
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https://hal.inrae.fr/hal-02750131
Contributor : Migration Prodinra <>
Submitted on : Wednesday, June 3, 2020 - 4:40:57 PM
Last modification on : Thursday, August 5, 2021 - 3:46:24 AM

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  • HAL Id : hal-02750131, version 1
  • PRODINRA : 348134

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Adriana Vanelli, Bernadette Banrezes, Thierry Sainte-Beuve, T.A.L. Brevini, Jean-Pierre Ozil. High or low cytosolyc NAD(P) during partthenogenetic activation does not induce aberrant centriole formation in the mouse. 4. COST Action FA0702 GEMINI General Conference - Maternal Comminication with Gametes and Embryo, Sep 2011, Gijon, Spain. COST Office European Cooperation in Science and Technology, 112 p., 2011, 4th General Meeting of GEMINI "Maternal Communication with Gametes and Embryo". ⟨hal-02750131⟩

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