Left-right gene expression asymmetry in gonads of rainbow trout, Oncorhynchus mykiss, following masculinization treatments with androgens
Résumé
Following masculinization of an all female genetic population of rainbow trout larvae by repetitive immersions with 17 alpha-methyltestosterone (17 alpha MT) we investigate if we could characterize a L/R gene expression asymmetry in the gonads of these treated fish. The 17 alpha MT immersion treatment resulted in an overall masculinization percentage of 29%. Gene expression of 18 genes reveals that most of the genes investigated exhibit clear left/right (L/R) differences in their gonadal expression profiles. This L/R asymmetry is probably the result of an early asymmetry of the gonad during the sex differentiation period.