Staphylococcus aureus-induced cytopathic effect on the mammalian cells
Résumé
Attention to the bacterial pathogenesis has increased in the past decade because of antibiotic resistance and recurrence of the old diseases. The precise knowledge of the mechanisms of bacteria-host interactions will help to develop the new effective therapeutics. Staphylococcus aureus is a major cause of a multitude of diseases including severe nosocomial and skin infections, as well as infectious mastitis in mammalian. It produces various virulence factors that induce the host cellular damage during infection. The aim of the study focus on the in vitro analysis of S. aureus cytopathic effects on the human and bovine epithelial cells