Soybean MON 877089MON 897889A5547-127 (three-event stack soybean) was produced byconventional crossing to combine three single events: MON 87708, MON 89788 and A5547-127. TheGMO Panel previously assessed the three single events and did not identify safety concerns. No newdata on the single events, leading to modification of the original conclusions on their safety have beenidentified. The molecular characterisation, comparative analysis (agronomic, phenotypic andcompositional characteristics) and the outcome of the toxicological, allergenicity and nutritionalassessment indicate that the combination of the single soybean events and of the newly expressedproteins in the three-event stack soybean does not give rise to food and feed safety and nutritionalconcerns. The GMO Panel concludes that the three-event stack soybean, as described in thisapplication, is as safe as and nutritionally equivalent to its conventional counterpart and the non-GMreference varieties tested. The nutritional impact of food/feed derived from the three-event stacksoybean is expected to be the same as that of food/feed derived from the conventional counterpartand non-GM reference varieties. In the case of accidental release of viable seeds of the three-eventstack soybean into the environment, this would not raise environmental safety concerns. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of thethree-event stack soybean. Post-market monitoring of food/feed is not considered necessary. The GMOPanel concludes that the three-event stack soybean is as safe as its conventional counterpart and thetested non-GM reference varieties with respect to potential effects on human and animal health andthe environment.