A clonally reproducing generalist aphid pest colonises diverse host plants by rapid transcriptional plasticity of duplicated gene clusters - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Preprints, Working Papers, ... (Preprint) Year : 2016

A clonally reproducing generalist aphid pest colonises diverse host plants by rapid transcriptional plasticity of duplicated gene clusters

Thomas Mathers
  • Function : Author
Yazhou Chen
  • Function : Author
Gemy Kaithakottil
  • Function : Author
Fabrice Legeai
Sam Mugford
  • Function : Author
Patrice Baa-Puyoulet
Anthony Bretaudeau
Bernardo Clavijo
  • Function : Author
Olivier Collin
Tamas Dalmay
  • Function : Author
Thomas Derrien
Honglin Feng
  • Function : Author
Toni Gabaldón
Anna Jordan
  • Function : Author
Irene Julca
  • Function : Author
Graeme Kettles
  • Function : Author
Krissana Kowitwanich
  • Function : Author
Dominique Lavenier
Paolo Lenzi
  • Function : Author
Sara Lopez-Gomollon
  • Function : Author
Damian Loska
  • Function : Author
Daniel Mapleson
  • Function : Author
Florian Maumus
Simon Moxon
  • Function : Author
Daniel Price
Akiko Sugio
Darren Waite
  • Function : Author
Georg Jander
  • Function : Author
Denis Tagu
Alex Wilson
  • Function : Author
Cock van Oosterhout
David Swarbreck
  • Function : Author
Saskia Hogenhout
  • Function : Author

Abstract

Background The prevailing paradigm of host-parasite evolution is that arms races lead to increasing specialisation via genetic adaptation. Insect herbivores are no exception, and the majority have evolved to colonise a small number of closely related host species. Remarkably, the green peach aphid, Myzus persicae , colonises plant species across 40 families and single M. persicae clonal lineages can colonise distantly related plants. This remarkable ability makes M. persicae a highly destructive pest of many important crop species. Results To investigate the exceptional phenotypic plasticity of M. persicae , we sequenced the M. persicae genome and assessed how one clonal lineage responds to host plant species of different families. We show that genetically identical individuals are able to colonise distantly related host species through the differential regulation of genes belonging to aphid-expanded gene families. Multigene clusters collectively up-regulate in single aphids within two days upon host switch. Furthermore, we demonstrate the functional significance of this rapid transcriptional change using RNA interference (RNAi)-mediated knock-down of genes belonging to the cathepsin B gene family. Knock-down of cathepsin B genes reduced aphid fitness, but only on the host that induced up-regulation of these genes. Conclusions Previous research has focused on the role of genetic adaptation of parasites to their hosts. Here we show that the generalist aphid pest M. persicae is able to colonise diverse host plant species in the absence of genetic specialisation. This is achieved through rapid transcriptional plasticity of genes that have duplicated during aphid evolution.

Dates and versions

hal-02936181 , version 1 (11-09-2020)

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Thomas Mathers, Yazhou Chen, Gemy Kaithakottil, Fabrice Legeai, Sam Mugford, et al.. A clonally reproducing generalist aphid pest colonises diverse host plants by rapid transcriptional plasticity of duplicated gene clusters. 2020. ⟨hal-02936181⟩
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