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Poster

Evidence for autophagy attenuation during post-mortem maturation of hypertrophied muscle in myostatin deficient mice

Abstract : The conversion of skeletal muscle into meat, i.e. maturation, is a complex process where muscle undergoes different biochemical and physiological changes (Ouali et al, 2006). In agronomic field, the study of these events is of particular interest, in order to improve the quality of the final product put on the market. If the characterization of the proteolytic mechanisms involved in skeletal muscle maturation is still ongoing, the participation of autophagy in this process is still under debate. The aim of the study was therefore to assess the involvement of autophagy during skeletal muscle maturation and to study the interaction between autophagy and myostatin, a negative regulator of skeletal muscle mass (Mc Pherron et al, 1997), within a 72h postmortem (PM) time frame in mice.
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https://hal.inrae.fr/hal-02940597
Déposant : Christelle Raynaud <>
Soumis le : mercredi 16 septembre 2020 - 13:55:22
Dernière modification le : jeudi 17 septembre 2020 - 03:35:45

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2017_Chabi_CFATG 2017 poster R...
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  • HAL Id : hal-02940597, version 1

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Rim Nassar, Barbara Vernus, Gilles Fouret, Benedicte Goustard, Francois Casas, et al.. Evidence for autophagy attenuation during post-mortem maturation of hypertrophied muscle in myostatin deficient mice. 7ème congrès du club français Autophagie CFATG, Nov 2017, Paris, France. 2017. ⟨hal-02940597⟩

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