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Article dans une revue

3D skin models in domestic animals

Abstract : The skin is a passive and active barrier which protects the body from the environment. Its health is essential for the accomplishment of this role. Since several decades, the skin has aroused a strong interest in various fields (for e.g. cell biology, medicine, toxicology, cosmetology, and pharmacology). In contrast to other organs, 3D models were mostly and directly elaborated in humans due to its architectural simplicity and easy accessibility. The development of these models benefited from the societal pressure to reduce animal experiments. In this review, we first describe human and mouse skin structure and the major differences with other mammals and birds. Next, we describe the different 3D human skin models and their main applications. Finally, we review the available models for domestic animals and discuss the current and potential applications.
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Article dans une revue
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https://hal.inrae.fr/hal-03146755
Déposant : Laurent Souci <>
Soumis le : lundi 22 février 2021 - 05:12:08
Dernière modification le : mardi 23 février 2021 - 08:47:52

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13567_2020_Article_888.pdf
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Distributed under a Creative Commons Paternité 4.0 International License

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Laurent Souci, Caroline Denesvre. 3D skin models in domestic animals. Veterinary Research, BioMed Central, 2021, 52 (1), 15 p. ⟨10.1186/s13567-020-00888-5⟩. ⟨hal-03146755⟩

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