While the benefit of silicon (Si) is often reported in cultivated plants, and particularly in those experiencing stress conditions, the underlying mechanisms are poorly described and controversial [1]. For a long time the mechanical role of Si in the cell wall has been considered as the main explanation for its beneficial effects in alleviating plant stresses. Another assumption is that a low proportion (around 1%) of the Si taken up by plants might modulate some metabolic pathways. Investigating this concept, Haddad et al. [2] demonstrated that in roots of Brassica napus plants, the modulation of a large range of genes by Si could explain an increased resistance to nitrogen (N) deficiency. However, since the Si benefit is mainly associated with maintaining photosynthetic activity and a delay in leaf senescence in the mature leaves of plants cultivated under N- deficiency [3], the aim of the present study was to identify (using a RNA sequencing approach) the transcriptomic modifications in the shoot compartment of +Si plants. Our results showed that there were 296 genes differentially expressed genes (DEGs)) in shoots of Brassica napus treated with Si (root supply 1.7 mM for 7 days). Among these genes, 19 and 31 upregulated genes were related to ribosomes and photosynthetic pathways, respectively. From these results, the assumption that a Si supply can facilitate efficient metabolic reinforcement and alleviate the biotic and abiotic stresses experienced by plants is discussed.