The epigenome of male germ cells and the programming of phenotypes in cattle

• Bull semen is a commercial product widely used for artificial insemination. • During the differentiation of male germ cells into spermatozoa, there are several windows of epigenome sensitivity to environmental factors. • The epigenome of bull sperm exhibits both conserved features and interindividual variations, some of which are associated with fertility. • The paternal epigenome contributes to embryo development and to programming the phenotype of offspring.

Keywords

DNA methylation cattle embryo development epigenetics male germ cells small noncoding RNAs

Domains

Reproductive Biology

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vfab062.pdf (31.03 Mo)

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Submitted on : Tuesday, May 31, 2022-9:00:43 AM

Last modification on : Saturday, May 13, 2023-4:21:31 AM

Dates and versions

hal-03508599 , version 1 (31-05-2022)

Licence

Attribution - CC BY 4.0

Identifiers

HAL Id : hal-03508599 , version 1
DOI : 10.1093/af/vfab062
PUBMED : 34934527
PUBMEDCENTRAL : PMC8683155
WOS : 000743301000005

Cite

Hélène Kiefer, Eli Sellem, Amélie Bonnet-Garnier, Maëlle Pannetier, Valentin Costes, et al.. The epigenome of male germ cells and the programming of phenotypes in cattle. Animal Frontiers, 2021, 11 (6), pp.28-38. ⟨10.1093/af/vfab062⟩. ⟨hal-03508599⟩

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