The epigenome of male germ cells and the programming of phenotypes in cattle

• Bull semen is a commercial product widely used for artificial insemination. • During the differentiation of male germ cells into spermatozoa, there are several windows of epigenome sensitivity to environmental factors. • The epigenome of bull sperm exhibits both conserved features and interindividual variations, some of which are associated with fertility. • The paternal epigenome contributes to embryo development and to programming the phenotype of offspring.

Mots clés

DNA methylation cattle embryo development epigenetics male germ cells small noncoding RNAs

Domaines

Biologie de la reproduction

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vfab062.pdf (31.03 Mo)

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https://hal.inrae.fr/hal-03508599

Soumis le : mardi 31 mai 2022-09:00:43

Dernière modification le : jeudi 11 janvier 2024-12:02:04

Dates et versions

hal-03508599 , version 1 (31-05-2022)

Licence

Paternité

Identifiants

HAL Id : hal-03508599 , version 1
DOI : 10.1093/af/vfab062
PUBMED : 34934527
PUBMEDCENTRAL : PMC8683155
WOS : 000743301000005

Citer

Hélène Kiefer, Eli Sellem, Amélie Bonnet-Garnier, Maëlle Pannetier, Valentin Costes, et al.. The epigenome of male germ cells and the programming of phenotypes in cattle. Animal Frontiers, 2021, 11 (6), pp.28-38. ⟨10.1093/af/vfab062⟩. ⟨hal-03508599⟩

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