Investigating and monitoring anthelmintic resistance: from molecular markers to High Throughput diagnosis tools - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement Access content directly
Conference Papers Year : 2022

Investigating and monitoring anthelmintic resistance: from molecular markers to High Throughput diagnosis tools

Élise Courtot
Fabrice Guégnard
  • Function : Author
  • PersonId : 1206399
Abdallah Harmache
Adrian Wolstenholme
  • Function : Author
Nicolas Lamassiaude
Morgane Miclon
  • Function : Author
  • PersonId : 1363982
Alexandre Vernudachi
  • Function : Author
Claude L. Charvet
Cédric Neveu

Abstract

The control of parasitic nematode infections in humans, livestock and companion animals is critically dependent on anthelmintic treatment. However, the indiscriminate use of anthelmintic drugs has inevitably led to the selection of resistant parasites. In this presentation, identification and functional validation of molecular markers associated with resistance will be presented, opening a discussion about advantages and limitations of the use of C. elegans as model for parasitic species. In addition, as diagnosis tools are of particular interest to monitor resistance spreading and refine strategies for the control resistant parasites, recent advances in automated phenotypic assays performed on larval stages of the parasite will be discussed
No file

Dates and versions

hal-04123782 , version 1 (09-06-2023)

Identifiers

  • HAL Id : hal-04123782 , version 1

Cite

Élise Courtot, Fabrice Guégnard, Abdallah Harmache, Adrian Wolstenholme, Nicolas Lamassiaude, et al.. Investigating and monitoring anthelmintic resistance: from molecular markers to High Throughput diagnosis tools. ANTHELMINTICS V, DRUGS, RESISTANCE & VACCINES, Pr Richard Martin, Pr Raffi Aroian, May 2022, Worcester (USA), United States. ⟨hal-04123782⟩
18 View
0 Download

Share

Gmail Mastodon Facebook X LinkedIn More