Quantitative microCT imaging of a whole equine placenta and its blood vessel network - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
Journal Articles Placenta Year : 2024

Quantitative microCT imaging of a whole equine placenta and its blood vessel network

Abstract

Placental structure is linked to function across morphological scales. In the placenta, changes to gross anatomy, such as surface area, volume, or blood vessel arrangement, are associated with suboptimal physiological outcomes. However, quantifying each of these metrics requires different laborious semi-quantitative methods. Here, we demonstrate how, with minimal sample preparation, whole-organ computed microtomography (microCT) can be used to calculate gross morphometry of the equine placenta and a range of additional metrics, including branching morphometry of placental vasculature, non-destructively from a single dataset. Our approach can be applied to quantify the gross structure of any large mammalian placenta.
Fichier principal
Vignette du fichier
1-s2.0-S0143400424006088-main.pdf (5.12 Mo) Télécharger le fichier
Origin Files produced by the author(s)
Licence

Dates and versions

hal-04678493 , version 1 (27-08-2024)

Licence

Identifiers

Cite

Davis Laundon, Ella Proudley, Philip J Basford, Orestis L Katsamenis, David S Chatelet, et al.. Quantitative microCT imaging of a whole equine placenta and its blood vessel network. Placenta, 2024, 154, pp.216-219. ⟨10.1016/j.placenta.2024.07.313⟩. ⟨hal-04678493⟩
10 View
2 Download

Altmetric

Share

More