Reducing the use of phytopharmaceutical products in vegetable production systems is one of the objectives of sustainable production. In both mainland France and the French West Indies, stakeholders are experimenting with various alternatives to pesticides, including biocontrol and biostimulants. However, the dissemination of these technologies remains limited and the substitution paradigm remains predominant, hindering the thorough redesign of cropping systems required for a successful ecological transition in agricultural production systems. We describe here a study performed in Guadeloupe, in which agricultural professionals were asked to identify obstacles and levers for the deployment of these biosolutions. We used different methodological sequences (diagnosis, exchange workshops, co-design workshops) and included a wide range of stakeholders (farmers, advisors, researchers, public stakeholders, agricultural suppliers) in this study, and we analysed the strategies of local stakeholders regarding the use of biosolutions. We found that real opportunities to move away from the substitution paradigm exist, but remain rare. We also found that the implementation of biosolutions requires a strengthening of local co-ordination between the various stakeholders in agrifood systems, to take agriculture along a true path of viable transformative change.