Shifting the limits in wheat research and breeding using a fully annotated reference genome - INRAE - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
Journal Articles Science Year : 2018

Shifting the limits in wheat research and breeding using a fully annotated reference genome

Michael Alaux
Françoise Alfama
  • Function : Author
  • PersonId : 1203741
Claire Guerche
  • Function : Author
  • PersonId : 1203743
Thomas Letellier
  • Function : Author
  • PersonId : 1203739
Mikaël Loaec
  • Function : Author
  • PersonId : 1203746
Hadi Quesneville
Rudi Appels
  • Function : Correspondent author
Philippe Rigault
  • Function : Author

Abstract

An annotated reference sequence representing the hexaploid bread wheat genome in 21 pseudomolecules has been analyzed to identify the distribution and genomic context of coding and noncoding elements across the A, B, and D subgenomes. With an estimated coverage of 94% of the genome and containing 107,891 high-confidence gene models, this assembly enabled the discovery of tissue- and developmental stage-related coexpression networks by providing a transcriptome atlas representing major stages of wheat development. Dynamics of complex gene families involved in environmental adaptation and end-use quality were revealed at subgenome resolution and contextualized to known agronomic single-gene or quantitative trait loci. This community resource establishes the foundation for accelerating wheat research and application through improved understanding of wheat biology and genomics-assisted breeding.

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Biotechnology

Dates and versions

hal-01885399 , version 1 (01-10-2018)

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. International Wheat Genome Sequencing Consortium (iwgsc), Arnaud Bellec, Helene Berges, Sonia Vautrin, Michael Alaux, et al.. Shifting the limits in wheat research and breeding using a fully annotated reference genome. Science, 2018, 361 (6403), pp.7191. ⟨10.1126/science.aar7191⟩. ⟨hal-01885399⟩
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